|Synonyms:||β-Phenyl-γ-aminobutyric acid, Aminophenylbutyric acid, 4-Amino-3-phenylbutanoic acid, Fenibut|
|Molecular Weight:||215.677 g/mol|
|Storage:||Store in a dry, dark, sealed container at room temperature.|
|Stability:||Stable at least for 2 years when stored probably.|
β-Phenyl-γ-aminobutyric acid (commonly known as Phenibut) is a depressant substance of the gabapentinoid class. Phenibut acts as a receptor agonist for GABA, the major inhibitory neurotransmitter in the brain.
Most phenibut is reported to be in the form of the hydrochloride salt (HCl). In this form, the phenibut is reacted with hydrochloric acid to form a stable, easily dissolvable, acidic, crystalline salt.
As a GABA derivative it has been shown that Phenibut acts as an agonist to the metabotropic GABA B receptor, with agonist action to the ionotropic GABA A receptor at higher doses.
Studies have also shown Phenibut to reduce levels of norepinephrine (adrenalin) within the hippocampus, helping reduce unwanted stimulation further. Antidepressant and anti-anxiety effects are likely due to the increase in reward neurotransmitter metabolites seen after Phenibut ingestion.