|Molecular Weight:||464.5 g/mol|
|Appearance:||White to off-white powder|
|Storage:||Store in a dry, dark, sealed container at room temperature.|
|Stability:||Stable at least for 2 years when stored probably.|
NSI-189 is an experimental, potential antidepressant that is under investigation by Neuralstem, Inc. for the treatment for major depressive disorder (MDD), as well as for cognitive impairment and neurodegeneration.
The mechanism of action of NSI-189 is not completely understood. Initial research suggests that this experimental drug may work by promoting neurogenesis, the growth of new nerve and brain cells. More specifically, NSI-189 appears to primarily affect the hippocampus, the part of the brain responsible for emotion, learning, and memory. In a cell study using human cells derived from the hippocampus, NSI-189 stimulated neurogenesis. A study using mice also suggests that NSI-189 may promote neurogenesis in the hippocampus.