|Synonyms:||(4-Amino-3-(4-fluorophenyl)butanoic acid hydrochloride, Fluorophenibut, 4-Fluorophenibut, CGP-11130|
|Molecular Weight:||233.663 g/mol|
|Molecular Formula:||C10FH12NO2 • HCl|
|Appearance:||White crystal powder|
|Storage:||Store in a dry, dark, sealed container at room temperature.|
|Stability:||Stable at least for 2 years when stored probably.|
4-Fluorophenibut (developmental code name CGP-11130; also known as β-(4-fluorophenyl)-γ-aminobutyric acid or β-(4-fluorophenyl)-GABA) is a GABAB receptor agonist which was never marketed. It is selective for the GABAB receptor over the GABAA receptor (IC50 = 1.70 µM and > 100 µM, respectively). The compound is a GABA analogue and is closely related to β-(4-chlorophenyl)-GABA, β-(4-methylphenyl)-GABA, and β-phenyl-GABA.
As with phenibut, F-Phenibut is a derivative of GABA, except with a fluorine-substituted phenyl group in the β-position of the molecule. It is a chiral molecule and thus has two potential configurations as (R)- and (S)-enantiomers.